ITPA ELISA kits are immunoassay tools for the measurement of the protein inosine triphosphatase, which is encoded by the ITPA gene in humans. Functionally, this protein is a reported pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The canonical protein structure is reported to have an amino acid length of 194 residues, a mass of 21.4 kDa, and is a member of the HAM1 NTPase protein family. It is known to be localized in the cytoplasm and is ubiquitously expressed across many tissue types. As many as 3 protein isoforms have been reported. The ITPA gene has been associated with the disease, Inosine triphosphate pyrophosphohydrolase deficiency. Other alias names for this target include DEE35, HLC14-06-P, ITPase, My049, NTPase, dJ794I6.3, inosine triphosphate pyrophosphatase, and C20orf37.
There are ITPA ELISA kits that can detect a target at concentrations as low as 0.1 ng/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.