Anti-PHYKPL antibodies are used in the immunodetection of the protein 5-phosphohydroxy-L-lysine phospho-lyase. In humans, the canonical protein has a reported length of 450 amino acid residues and a mass of 49.7 kDa. Its subcellular localization is in the mitochondria. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Class-III pyridoxal-phosphate-dependent aminotransferase protein family, Phykpl is known to catalyze the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. The PHYKPL gene has been associated with the disease, Phosphohydroxylysinuria. Synonyms for this target antigen include 5-phosphonooxy-L-lysine phospho-lyase and alanine--glyoxylate aminotransferase 2-like 2. PHYKPL gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Some Phykpl antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.