Anti-GID8 antibodies are used in the immunodetection of the protein GID complex subunit 8 homolog. In humans, the canonical protein has a reported length of 228 amino acid residues and a mass of 26.7 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is notably widely expressed in many tissue types. A member of the GID8 protein family, GID8 is an important component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Synonyms for this target antigen include TWA1, glucose-induced degradation protein 8 homolog, protein C20orf11, two hybrid associated protein No. 1 with RanBPM, two hybrid-associated protein 1 with RanBPM, and C20orf11. GID8 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of GID8 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.