Anti-CYB561A3 antibodies are used in the immunodetection of the protein cytochrome b561 family member A3. In humans, the canonical protein has a reported length of 242 amino acid residues and a mass of 27.2 kDa. Its subcellular localization is in the lysosomes. Up to 2 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the adrenal gland and gallbladder. CYB561A3 is reported to be a transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce iron cations Fe(3+) into Fe(2+) in the lumen of the late endosome and lysosome. Synonyms for this target antigen include cytochrome b ascorbate-dependent protein 3, cytochrome b, ascorbate dependent 3, lysosomal cytochrome b, and lysosomal membrane ascorbate-dependent ferrireductase CYB561A3. CYB561A3 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. Indicated applications for CYB561A3 antibodies listed below include ELISA, Flow Cytometry, Western Blot, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry.