Anti-ISCU antibodies are used in the immunodetection of the protein iron-sulfur cluster assembly enzyme. In humans, the canonical protein has a reported length of 167 amino acid residues and a mass of 18 kDa. Its subcellular localization is in the nucleus, mitochondria, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in fetal liver, skeletal muscle, brain, pancreas, kidney, lung and placenta. A member of the NifU protein family, ISCU is known to be involved with electron transport. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include HML, ISU2, NIFU, NIFUN, hnifU, and 2310020H20Rik. ISCU gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ISCU antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.