Anti-TLE2 antibodies are used in the immunodetection of the protein TLE family member 2, transcriptional corepressor. In humans, the canonical protein has a reported length of 743 amino acid residues and a mass of 79.8 kDa. Its subcellular localization is in the nucleus. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the WD repeat Groucho/TLE protein family, TLE2 is reported to be a transcriptional corepressor that binds to a number of transcription factors. Synonyms for this target antigen include ESG2, GRG2, transducin-like enhancer protein 2, enhancer of split groucho-like protein 2, and ESG. TLE2 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. A number of TLE2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.