Anti-CPAMD8 antibodies are used in the immunodetection of the protein C3 and PZP like alpha-2-macroglobulin domain containing 8. In humans, the canonical protein has a reported length of 1885 amino acid residues and a mass of 206.7 kDa. Its subcellular localization is in the cell membrane and is secreted. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the kidney, brain and testis and to a lower extent in the heart, liver and small intestine. A member of the Protease inhibitor I39 (alpha-2-macroglobulin) protein family, CPAMD8 is known to be involved with eye development. Post-translational modifications have been described, including protein cleavage and glycosylation. Synonyms for this target antigen include K-CAP, VIP, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8, alpha-2 macroglobulin family protein VIP, and ASGD8. CPAMD8 gene orthologs have been reported in the bovine, frog, zebrafish, chimpanzee and chicken species. These CPAMD8 antibodies are widely used in Immunohistochemistry experiments, among other applications.