Anti-C9orf78 antibodies are used in the immunodetection of the protein chromosome 9 open reading frame 78. In humans, the canonical protein has a reported length of 289 amino acid residues and a mass of 33.7 kDa. Its subcellular localization is in the nucleus. It is notably widely expressed in many tissue types. A member of the TLS1 protein family, C9orf78 is reported to play a role in pre-mRNA splicing by promoting usage of the upstream 3'-splice site at alternative NAGNAG splice sites; these are sites featuring alternative acceptor motifs separated by only a few nucleotides. Synonyms for this target antigen include HCA59, HSPC220, TLS1, bA409K20.3, splicing factor C9orf78, and CSU2. C9orf78 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some C9orf78 antibodies may have been used in research and have associated citations. Western Blot, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are common applications for these antibodies.