Anti-TMEM109 antibodies are used in the immunodetection of the protein transmembrane protein 109. In humans, the canonical protein has a reported length of 243 amino acid residues and a mass of 26.2 kDa. Its subcellular localization is in the nucleus and ER. It is notably widely expressed in many tissue types. TMEM109 is believed to mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death. Synonyms for this target antigen include mg23 and mitsugumin-23. TMEM109 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. Some TMEM109 antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.