Anti-TGUT antibodies are used in antigen-specific immunodetection in biological samples. The target TGUT is a known alias name of the protein queuine tRNA-ribosyltransferase catalytic subunit 1, encoded by the QTRT1 gene in humans. This 403-amino acid residue protein is a known catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). It is localized to the membrane, mitochondria, and cytoplasm of the cell. It is reported to be expressed in many tissues, such as the cerebral cortex, testis, and adrenal gland. Indicated applications for TGUT antibodies listed below include ELISA and Western Blot.