Anti-Tetraspanin 14 antibodies are used in the immunodetection of the protein encoded by the TSPAN14 gene. In humans, the canonical protein has a reported length of 270 amino acid residues and a mass of 30.7 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of the Tetraspanin (TM4SF) protein family, it is reported to regulate maturation and trafficking of the transmembrane metalloprotease ADAM10. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include tetraspanin similar to TM4SF9 and transmembrane 4 superfamily member 14.