Anti-MELF antibodies are protein reagents that detect specific antigens. The MELF antigen is another term for the human protein EPM2A glucan phosphatase, laforin, encoded by the EPM2A gene. The protein is known to play an important role in preventing glycogen hyperphosphorylation and the formation of insoluble aggregates, via its activity as glycogen phosphatase, and by promoting the ubiquitination of proteins involved in glycogen metabolism via its interaction with the E3 ubiquitin ligase NHLRC1/malin. Canonically, it has an amino acid length of 331 residues and a mass of 37.2 kilodaltons. Its subcellular localization is in the cytoplasm and it is found to be expressed in the heart, skeletal muscle, kidney, pancreas and brain. The MELF protein is a member of the Protein-tyrosine phosphatase protein family. Other alias names for MELF include EPM2 and laforin. These MELF antibodies are widely used in Western Blot experiments, among other applications.