Anti-HSE1 antibodies are protein reagents that detect specific antigens. The HSE1 antigen is another term for the human protein heparanase, encoded by the HPSE gene. The protein is a reported endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Canonically, it has an amino acid length of 543 residues and a mass of 61.1 kilodaltons. Its subcellular localization is in the nucleus, lysosomes, membrane, and is secreted. It is reported to be highly expressed in the placenta and spleen and weakly expressed in lymph node, thymus, peripheral blood leukocytes, bone marrow, endothelial cells, fetal liver and tumor tissues. The HSE1 protein is a member of the Glycosyl hydrolase 79 protein family. Other alias names for HSE1 include HPA, HPA, and HPA1. Some HSE1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.