Anti-HHS antibodies are used in antigen-specific immunodetection in biological samples. The target HHS is a known alias name of the protein polypeptide N-acetylgalactosaminyltransferase 3, encoded by the GALNT3 gene in humans. This 633-amino acid residue protein is known to catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. It is localized to the Golgi of the cell and features glycosylated post-translational modifications. In terms of tissue expression, it is reported to be expressed in organs that contain secretory epithelial glands.