Anti-HCCR-2 antibodies are used in antigen-specific immunodetection in biological samples. The target HCCR-2 is a known alias name of the protein LETM1 domain containing 1, encoded by the LETMD1 gene in humans. This 360-amino acid residue protein is known to play an important role for mitochondrial structure and function, as well as thermogenesis of brown adipocytes. It is localized to the nucleus and mitochondria of the cell.