Anti-GNAQ antibodies are used in the immunodetection of the protein G protein subunit alpha q. In humans, the canonical protein has a reported length of 359 amino acid residues and a mass of 42.1 kDa. Its subcellular localization is in the nucleus, Golgi, and cell membrane. It is reported to be highly expressed in the ovary, prostate, testis and colon. A member of the G-alpha protein family, GNAQ is known to be involved with GPCR signaling pathways and protein stabilization. Post-translational modifications have been described, including palmitoylation. The GNAQ gene has been associated with the disease, Capillary malformations. Synonyms for this target antigen include CMC1, G-ALPHA-q, GAQ, SWS, guanine nucleotide-binding protein G(q) subunit alpha, and CMAL. GNAQ gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.