Anti-Aco3 antibodies are protein reagents that detect specific antigens. The Aco3 antigen is another term for the human protein iron responsive element binding protein 2, encoded by the IREB2 gene. The protein is reported to be a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Canonically, it has an amino acid length of 963 residues and a mass of 105.1 kilodaltons. Its subcellular localization is in the cytoplasm. The Aco3 protein is a member of the Aconitase/IPM isomerase protein family. Other alias names for Aco3 include IRE-BP 2. Western Blot is the most common application for the Aco3 antibodies listed below. ELISA and Immunohistochemistry are also common applications.