Anti-cytolysin antibodies enable researchers to detect and measure the cytolysin antigen in biological samples. This target is a reported synonym of the PRF1 gene, which encodes perforin 1. This protein is known to function in the apoptotic pathway and viral immune response, among other biological roles. The human version of cytolysin has a canonical amino acid length of 555 residues and a protein mass of 61.4 kilodaltons. It is reported to be localized in the cell membrane and is secreted of cells and notably expressed in the spleen, oral mucosa, lymph node, esophagus, and endometrium. Other names for this target antigen include HPLH2, P1, and PFP. Some cytolysin antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.