Anti-espin like antibodies are used in the immunodetection of the protein encoded by the ESPNL gene. In humans, the canonical protein has a reported length of 1005 amino acid residues and a mass of 108.1 kDa. Its subcellular localization is in the cell projections. Alternative splicing is reported to yield 3 different isoforms for this protein. It is known to bind to but does not cross-link actin. Other names for this target antigen include espin-like protein.