Anti-DENND2B antibodies are used in the immunodetection of the protein DENN domain containing 2B. In humans, the canonical protein has a reported length of 1137 amino acid residues and a mass of 126.5 kDa. Its subcellular localization is in the cell membrane, cytoplasmic vesicles, and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be widely expressed with the exception of peripheral blood lymphocytes. DENND2B is suspected to be involved in cytoskeletal organization and tumorogenicity. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include ST5, p126, DENN domain-containing protein 2B, DENN/MADD domain containing 2B, heLa tumor suppression 1, and HTS1. DENND2B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some DENND2B antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.