HEI10, or Cyclin B1 interacting protein 1, E3 ubiquitin protein ligase, is a human gene encoded by CCNB1IP1. It may also be known as: E3 ubiquitin-protein ligase CCNB1IP1; Cyclin-B1-interacting protein 1; Human enhancer of invasion 10; E3 ubiquitin-protein ligase CCNB1IP1 ; C14orf18. The encoded protein is an enzyme with an amino acid length of 277 and a mass of 31.5 kDa. Other isoforms may exist. Homologs of this gene exist in other organisms, including: Frog.