Anti-SARS1 antibodies are used in the immunodetection of the protein seryl-tRNA synthetase 1. In humans, the canonical protein has a reported length of 514 amino acid residues and a mass of 58.8 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is notably expressed in the brain. A member of the Class-II aminoacyl-tRNA synthetase protein family, Sars1 is known to catalyze the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Synonyms for this target antigen include SARS, SERS, serine--tRNA ligase, cytoplasmic, serine tRNA ligase 1, cytoplasmic, and NEDMAS. SARS1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 120 citations in the literature describe the use of Sars1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.