Anti-C2orf48 antibodies enable researchers to detect and measure the C2orf48 antigen in biological samples. This target is a reported synonym of the RRM2 gene, which encodes ribonucleotide reductase regulatory subunit M2. This protein is known to function in DNA replication, among other biological roles. The human version of C2orf48 has a canonical amino acid length of 389 residues and a protein mass of 44.9 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the nucleus and cytoplasm of cells and notably expressed in the small intestine, rectum, duodenum, colon, and appendix. C2orf48 is a member of the Ribonucleoside diphosphate reductase small chain protein family.