Anti-GPS2 antibodies are used in the immunodetection of the protein G protein pathway suppressor 2. In humans, the canonical protein has a reported length of 327 amino acid residues and a mass of 36.7 kDa. Its subcellular localization is in the nucleus, mitochondria, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is widely expressed across many tissue types. GPS2 is a reported key regulator of inflammation, lipid metabolism and mitochondrion homeostasis that acts by inhibiting the activity of the ubiquitin-conjugating enzyme UBE2N/Ubc13, thereby inhibiting 'Lys-63'-linked ubiquitination (By similarity). Synonyms for this target antigen include AMF-1. GPS2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some GPS2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.