Anti-GDE3 antibodies enable researchers to detect and measure the GDE3 antigen in biological samples. This target is a reported synonym of the GDPD2 gene, which encodes glycerophosphodiester phosphodiesterase domain containing 2. This protein is known to function in the metabolism of lipids and osteoblast differentiation, among other biological roles. The human version of GDE3 has a canonical amino acid length of 539 residues and a protein mass of 61.7 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the cell membrane and cytoplasm of cells. GDE3 is a member of the Glycerophosphoryl diester phosphodiesterase protein family.