Anti-IRAG antibodies enable researchers to detect and measure the IRAG antigen in biological samples. This target is a reported synonym of the IRAG1 gene, which encodes inositol 1,4,5-triphosphate receptor associated 1. This protein is reported to play a role in as NO/PRKG1-dependent regulator of IP3-induced calcium release; its phosphorylation by PRKG1 inhibits bradykinin and IP3-induced calcium release from intracellular stores. The human version of IRAG has a canonical amino acid length of 904 residues and a protein mass of 98 kilodaltons, although 9 isoforms have been identified. It is reported to be localized in the cytoplasm of cells.