Anti-Iduna antibodies enable researchers to detect and measure the Iduna antigen in biological samples. This target is a reported synonym of the RNF146 gene, which encodes ring finger protein 146. This protein is known to function in the Wnt signaling pathway, among other biological roles. The human version of Iduna has a canonical amino acid length of 359 residues and a protein mass of 39 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the nucleus and cytoplasm of cells and widely expressed in many tissue types. Other names for this target antigen include E3 ubiquitin-protein ligase RNF146, RING-type E3 ubiquitin transferase RNF146, and dactylidin.