Anti-AARS2 antibodies are used in the immunodetection of the protein alanyl-tRNA synthetase 2, mitochondrial. In humans, the canonical protein has a reported length of 985 amino acid residues and a mass of 107.3 kDa. Its subcellular localization is in the mitochondria. It is notably widely expressed in many tissue types. A member of the Class-II aminoacyl-tRNA synthetase protein family, AARS2 is known to catalyze the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Synonyms for this target antigen include alanine tRNA ligase 2, mitochondrial (putative), alanyl-tRNA synthetase 2, mitochondrial (putative), alanyl-tRNA synthetase like, and alanine--tRNA ligase, mitochondrial. AARS2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some AARS2 antibodies may have been used in research and have associated citations. Immunohistochemistry is a widely used application for these antibodies. Western Blot and Immunofluorescence are also common applications.