Anti-SUN5 antibodies are used in the immunodetection of the protein Sad1 and UNC84 domain containing 5. In humans, the canonical protein has a reported length of 379 amino acid residues and a mass of 43.1 kDa. Its subcellular localization is in the nucleus and Golgi. It is notably expressed in the testis. SUN5 is known to play an important role in anchoring sperm head to the tail. Post-translational modifications have been described, including glycosylation. The SUN5 gene has been associated with the disease, Spermatogenic failure. Synonyms for this target antigen include epididymis secretory sperm binding protein, sad1 and UNC84 domain-containing protein 5, sperm-associated antigen 4-like protein, and SUN domain-containing protein 5. SUN5 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. A number of SUN5 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.