Anti-SMTNL1 antibodies are used in the immunodetection of the protein smoothelin like 1. In humans, the canonical protein has a reported length of 494 amino acid residues and a mass of 53 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is reported to be expressed in striated muscles, specifically in type 2a fibers. A member of the Smoothelin protein family, Smtnl1 is reported to play a role in the regulation of contractile properties of both striated and smooth muscles. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include smoothelin-like protein 1 and calponin homology-associated smooth muscle protein. SMTNL1 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Some Smtnl1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.