Anti-SYNPO2 antibodies are used in the immunodetection of the protein synaptopodin 2. In humans, the canonical protein has a reported length of 1093 amino acid residues and a mass of 117.5 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 5 different isoforms have been reported for this protein. It is reported to be expressed in the heart muscle. A member of the Synaptopodin protein family, SYNPO2 is known to have an actin-binding and actin-bundling activity. Post-translational modifications have been described, including phosphorylation.
The SYNPO2 marker can be used to identify Mesangial Cells.* Synonyms for this target antigen include genethonin-2, myopodin, and SYNPO2 intron sense-overlapping lncRNA. SYNPO2 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of SYNPO2 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA, Western Blot, Immunocytochemistry, and Immunofluorescence are also common applications.
*HuBMAP Human Reference Atlas v1.4