Anti-SLC6A13 antibodies are used in the immunodetection of the protein solute carrier family 6 member 13. In humans, the canonical protein has a reported length of 602 amino acid residues and a mass of 68 kDa. Its subcellular localization is in the cell membrane. Up to 3 different isoforms have been reported for this protein. It is reported to be expressed in the brain, kidney, lung, liver and testis. A member of the Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) protein family, SLC6A13 is known to mediate sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA).
The SLC6A13 marker can be used to identify Brain Vascular Non-Neuronal Cells.* Synonyms for this target antigen include GAT2, GAT3, sodium- and chloride-dependent GABA transporter 2, GABA transport protein, and GAT-2. SLC6A13 gene orthologs have been reported in the mouse, rat and bovine species. A number of SLC6A13 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4