Anti-phospholipase C, beta 3 (phosphatidylinositol-specific) antibodies enable researchers to detect and measure the phospholipase C, beta 3 (phosphatidylinositol-specific) antigen in biological samples. This target is a reported synonym of the PLCB3 gene, which encodes phospholipase C beta 3. This protein is known to function in GPCR signaling pathways and the metabolism of lipids, among other biological roles. The human version of phospholipase C, beta 3 (phosphatidylinositol-specific) has a canonical amino acid length of 1234 residues and a protein mass of 138.8 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the nucleus and cytoplasm of cells and notably expressed in the small intestine, kidney, duodenum, cerebellum, and appendix. Other names for this target antigen include SMDCD, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, and PLC beta 3.