Anti-PARN antibodies are used in the immunodetection of the protein poly(A)-specific ribonuclease. In humans, the canonical protein has a reported length of 639 amino acid residues and a mass of 73.5 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the CAF1 protein family, PARN is a reported 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Synonyms for this target antigen include DKCB6, PFBMFT4, poly(A)-specific ribonuclease PARN, deadenylating nuclease, deadenylation nuclease, and DAN. PARN gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of PARN antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.