Anti-HLA-DQB2 antibodies are used in the immunodetection of the protein major histocompatibility complex, class II, DQ beta 2. In humans, the canonical protein has a reported length of 268 amino acid residues and a mass of 30.4 kDa. Its subcellular localization is in the ER, Golgi, lysosomes, and cell membrane. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the skin. A member of the MHC class II protein family, HLA-DQB2 is known to bind peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. Synonyms for this target antigen include HLA-DQB1, HLA-DXB, HLA class II histocompatibility antigen, DQ beta 2 chain, DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB)), and DQB2. Over 120 citations in the literature describe the use of HLA-DQB2 antibodies in research. These antibodies are most commonly used in Western Blot experiments, among other applications.