Anti-OBSCN antibodies are used in the immunodetection of the protein obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. In humans, the canonical protein has a reported length of 7968 amino acid residues and a mass of 868.5 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 5 different isoforms for this protein. A member of a the CAMK Ser/Thr protein kinase protein family, OBSCN is reported to be a structural component of striated muscles which plays a role in myofibrillogenesis. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include obscurin, myosin light chain kinase, obscurin-MLCK, and obscurin.