Anti-MSH4 antibodies are used in the immunodetection of the protein mutS homolog 4. In humans, the canonical protein has a reported length of 936 amino acid residues and a mass of 104.8 kDa. Its subcellular localization is in the chromosomes. It is reported to be highly expressed in the testis. A member of the DNA mismatch repair MutS protein family, MSH4 is known to be involved in meiotic recombination. The MSH4 gene has been associated with the disease, Spermatogenic failure. Synonyms for this target antigen include POF20, SPGF2, mutS protein homolog 4, hMSH4, and ASG. MSH4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some MSH4 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.