Anti-IRAK1BP1 antibodies are used in the immunodetection of the protein interleukin 1 receptor associated kinase 1 binding protein 1. In humans, the canonical protein has a reported length of 260 amino acid residues and a mass of 29.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. A member of the IRAK1BP1 protein family, IRAK1BP1 is a known component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include ActA binding protein 3 and IRAK1-binding protein 1. IRAK1BP1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.