Anti-Docking Protein 5 antibodies are used for the immunodetection of the protein encoded by the DOK5 gene. In humans, the canonical protein has a reported length of 306 amino acid residues and a mass of 35.5 kDa. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be highly expressed in skeletal muscle, lower in the brain, heart and kidney. A member of the DOK protein family, it is known to be involved with the regulation of cell differentiation and MAPK cascade signaling pathways. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include downstream of tyrosine kinase 5 and insulin receptor substrate 6. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some Docking Protein 5 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.