Anti-BMP6 antibodies are used in the immunodetection of the protein bone morphogenetic protein 6. In humans, the canonical protein has a reported length of 513 amino acid residues and a mass of 57.2 kDa. It has been described to be a secreted protein. A member of the TGF-beta protein family, BMP6 is reported to be a growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation. Post-translational modifications have been described, including glycosylation.
The BMP6 marker can be used to identify Cerebral Cortex MGE Interneurons and Thalamic Excitatory Neurons.* Synonyms for this target antigen include VGR, VGR1, VG-1-R, VG-1-related protein, vegetal related growth factor (TGFB-related), and IO. BMP6 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of BMP6 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4