Anti-cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa antibodies enable researchers to detect and measure the cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa antigen in biological samples. This target is a reported synonym of the CSTF3 gene, which encodes cleavage stimulation factor subunit 3. This protein is reported to be one of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. The human version of cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa has a canonical amino acid length of 717 residues and a protein mass of 82.9 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the nucleus of cells and widely expressed in many tissue types. Other names for this target antigen include CSTF-77, CF-1 77 kDa subunit, and CSTF 77 kDa subunit.