Anti-TMEM63C antibodies are used in the immunodetection of the protein transmembrane protein 63C. In humans, the canonical protein has a reported length of 806 amino acid residues and a mass of 93.3 kDa. Its subcellular localization is in the cell membrane. It is reported to be expressed in podocytes of kidney glomeruli. A member of the CSC1 (TC 1.A.17) protein family, TMEM63C is known to act as a osmosensitive calcium-permeable cation channel. The TMEM63C gene has been associated with the disease, Spastic paraplegia. Synonyms for this target antigen include calcium permeable stress-gated cation channel 1 homolog, and calcium permeable stress-gated cation channel 1. TMEM63C gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some TMEM63C antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.