Anti-RNASEH2A antibodies are used in the immunodetection of the protein ribonuclease H2 subunit A. In humans, the canonical protein has a reported length of 299 amino acid residues and a mass of 33.4 kDa. Its subcellular localization is in the nucleus. A member of the RNase HII protein family, RNASEH2A is a known catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. The RNASEH2A gene has been associated with the disease, Aicardi-Goutieres syndrome. Synonyms for this target antigen include JUNB, RNASEHI, RNHIA, RNHL, THSD8, RNase H(35), RNase H2 subunit A, and AGS4. RNASEH2A gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. A number of RNASEH2A antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, and Immunohistochemistry are also common applications.