Anti-RXFP2 antibodies are used in the immunodetection of the protein relaxin family peptide receptor 2. In humans, the canonical protein has a reported length of 754 amino acid residues and a mass of 86.5 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow. A member of the G-protein coupled receptor 1 protein family, RXFP2 is a known receptor for relaxin.
The RXFP2 marker can be used to identify Amygdala Excitatory Neurons.* Synonyms for this target antigen include G protein coupled receptor affecting testicular descent, G-protein coupled receptor 106, leucine-rich repeat-containing G-protein coupled receptor 8, and relaxin receptor 2. RXFP2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. A number of RXFP2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4