Anti-PLXDC2 antibodies are used in the immunodetection of the protein plexin domain containing 2. In humans, the canonical protein has a reported length of 529 amino acid residues and a mass of 59.6 kDa. Its subcellular localization is in the membrane. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue. A member of a the Plexin protein family, PLXDC2 is believed to play a role in tumor angiogenesis. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include 1200007L24Rik, tumor endothelial marker 7-related protein, and plexin domain-containing protein 2.