Anti-NR2B antibodies are used in antigen-specific immunodetection in biological samples. The target NR2B is a known alias name of the protein glutamate ionotropic receptor NMDA type subunit 2B, encoded by the GRIN2B gene in humans. This 1484-amino acid residue protein is known to be a component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. It is localized to the cell membrane, lysosomes and cytoplasm of the cell and features phosphorylated and glycosylated post-translational modifications. It is reported to be expressed in the cerebellum. Other synonyms for NR2B include DEE27, EIEE27, and GluN2B. Some NR2B antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.