Anti-TUB like protein 4 antibodies are used for the immunodetection of the protein encoded by the TULP4 gene. In humans, the canonical protein has a reported length of 1543 amino acid residues and a mass of 169 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is notably expressed in the brain, skeletal muscle, testis and kidney. A member of the TUB protein family, it is believed to be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Other names for this target antigen include tubby like protein 4, tubby super-family protein, tubby superfamily protein, and tubby-related protein 4. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.