Anti-trafficking regulator and scaffold protein tamalin antibodies are used for the immunodetection of the protein encoded by the TAMALIN gene. In humans, the canonical protein has a reported length of 395 amino acid residues and a mass of 42.6 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to play a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. Other names for this target antigen include GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein, general receptor for phosphoinositides 1 associated scaffold protein, and protein TAMALIN. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.