Anti-H1.1 linker histone, cluster member antibodies are used for the immunodetection of the protein encoded by the H1-1 gene. In humans, the canonical protein has a reported length of 215 amino acid residues and a mass of 21.8 kDa. Its subcellular localization is in the nucleus. A member of the Histone H1/H5 protein family, it is known to be involved with spermatogenesis. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include H1A, H1F1, HIST1, HIST1H1A, histone H1.1, H1 histone family, member 1, histone 1, H1a, and H1.1. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species.