Anti-centrosomal AT-AC splicing factor antibodies are used for the immunodetection of the protein encoded by the CENATAC gene. In humans, the canonical protein has a reported length of 332 amino acid residues and a mass of 38 kDa. Its subcellular localization is in the cytoplasm. It is a known component of the minor spliceosome that promotes splicing of a specific, rare minor intron subtype. Post-translational modifications have been described, including acetylation. The gene encoding this protein is implicated in Mosaic variegated aneuploidy syndrome. Other names for this target antigen include coiled-coil domain containing 84 and coiled-coil domain-containing protein 84. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.